Yes. Polycystic ovary syndrome (PCOS) increases the risk of first-trimester miscarriage, which may be linked to poor egg quality and a suboptimal endometrial environment. Additionally, obesity further increases the risk of early miscarriage, making weight management an important consideration before conception.  

Pregnancy in women with PCOS often requires closer monitoring, as it is associated with a higher risk of gestational diabetes and hypertension, both of which can lead to complications for both the mother and baby. Proper medical supervision and lifestyle adjustments can help manage these risks effectively.