How Does Embryo Transfer Work?  

Feb 5, 2025

Fertility

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Embryo transfer is a critical step in IVF success, requiring close coordination between the fertility specialist and the embryologist.  

Timing of the Transfer  

  • Usually performed between Day 2 and Day 5 after egg retrieval for a fresh embryo transfer.  

  • The exact day depends on embryo development and clinic protocol.  

The Procedure  

1. Preparation
  • The woman is positioned in a gynecological exam chair.  

  • A speculum is inserted to expose the cervix.  

  • The cervix is gently cleaned, and any excess cervical mucus is removed. 

2. Embryo Transfer Process 
  • A trial transfer may be done first with an empty catheter to ensure smooth entry into the uterus. Some clinics perform this test in a prior consultation or on egg retrieval day.  

  • The selected embryo(s) are placed in a thin catheter attached to a syringe.  

  • Under ultrasound guidance, the catheter is carefully inserted through the cervical canal into the uterine cavity.  

  • The embryo(s) are deposited 1 to 1.5 cm from the top of the uterus, optimizing implantation potential.  

3. Post-Transfer Check
  • The catheter is removed and checked by the embryologist to ensure no embryo remains inside.  

  • If an embryo stays in the catheter, the procedure is repeated immediately with no impact on success rates.  

Optimizing the Procedure  

  • A semi-full bladder is recommended, as it gently shifts the uterus into a better position for catheter insertion.  

  • The procedure is painless for most women and does not require anesthesia, though some women with cervical sensitivity may experience mild discomfort.  

  • If local or general anesthesia is used, it does not reduce pregnancy success rates.  

  • Embryo transfer is a quick, delicate, and precise procedure, maximizing the chances of implantation.

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